Balloon Cell Urethral Melanoma: Differential Diagnosis and Management
Balloon Cell Urethral Melanoma: Differential Diagnosis and Management
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Introduction.Primary malignant melanoma of the urethra is a rare tumour (0.2% of all melanomas) that most commonly affects the 5 Piece Outdoor Firepit Chat Set meatus and distal urethra and is three times more common in women than men.Case.A 76-year-old lady presented with vaginal pain and discharge.
On examination, a 4 cm mass was noted in the vagina and biopsy confirmed melanoma of a balloon type.Preoperative CT showed no distant metastases and an MRI scan of the pelvis demonstrated no associated lymphadenopathy.She underwent anterior exenterative surgery and vaginectomy also.Histology confirmed a urethral nodular malignant melanoma.Discussion.
First-line treatment of melanoma is often surgical.Adjuvant treatment including chemotherapy, radiotherapy, or immunotherapy has also been reported.Even with aggressive management, malignant melanoma of the urogenital tract generally has a poor prognosis.Recurrence rates are high and the mean period between diagnosis and recurrence is 12.5 months.
A 5-year survival rate of less Framed Canvas than 20% has been reported in balloon cell melanomas along with nearly 20% developing local recurrence.Conclusion.To the best of our knowledge, this case is the first report of balloon cell melanoma arising in the urethra.The presentation and surgical management has been described and a literature review provided.